That way, your doctor can check on any potential side effects or interactions with medications. What Is Pycnogenol, and What's It Used For? - Wonder Labs Commonly called arthritis, osteoarthritis is caused when the cartilage on your joints begins to wear down. By clicking Subscribe, I agree to the WebMD, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox, Becoming a Vegetarian: Foods to Choose From. A study of 58 people with high blood pressure suggests that even lower doses (100 mg/day) may improve blood vessel health and reduce markers of high blood pressure (endothelin-1) after 12 weeks. Although these may still be high quality, the active compounds are more likely to vary. Start with a low dose so you can be sure it doesnt cause any side effects. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox. The authors attributed the negative results to the short duration of treatment and the low dosages of drug or Pycnogenol. Lets begin with asthma. It seems to lower blood pressure and improve blood flow to the legs. Pycnogenol is a substance taken from the pine bark of trees found in the southwest region of France. A study was conducted by the Guang An Men Hospital of Chinese Medical Science Research Institutewith 77 diabetes type II patients to determine if theextract of the French Maritime pine bark provided anti-diabetic effects. Pycnogenol (100 mg/day) may reduce leg swelling, spider veins, and cramps according to a study of 133 women with varicose veins who recently gave birth. All included participants had subclinical cognitive impairment, which looks like typical brain fog [22]. Pycnogenol is a patented formulation of Pine Bark Extract which is standardized to 65-75% Procyanidin compounds by weight. This study adds to a body of research showing the benefits of Pycnogenol . It should never be used as a replacement for approved medical therapies. Grape seed extract may be more beneficial for those who are obese. So begins my look at the natural supplement, pycnogenol (French Maritime Pine Bark Extract)benefits. Additionally, the results showed that the extract has significant anti-pseudomonas activity, making it a potential natural remedy and possible preventive measure for infections. (2013). Skin irritation. Pycnogenol in metabolic syndrome and related disorders [Abstract]. This study adds to a body of research showing the benefits of Pycnogenol for improving circulation and blood flow, strengthening the vascular system and managing cholesterol. Dr. Steven Lamm did a great job at explaining the new benefits of pycnogenol. The same study showed that a single, 200-mg Pycnogenol dose remained effective over six days in preventing cigarette-induced enhanced platelet aggregation. Study participants took pine bark extract as a supplement, and it was found to be most effective in women who started out with dry skin. It decreased concussion symptoms in 42 student-athletes with a history of sports-related concussions after 6 weeks. Forty patients were treated with either 600 mg chestnut seed extract a day or 360 mg Pycnogenol a day over a period of four weeks. Health Benefits of L-Arginine - WebMD In the study, it reduced cold symptoms and complications, the number of lost working days, and the use of over-the-counter medications compared to those who did not supplement with the extract [60]. Various brands of pycnogenol are available. The review found evidence that pine bark extract may: Similar to its neuroprotective benefits, the metabolic benefits of pine bark extract seem to be related to its antioxidant and anti-inflammatory properties. (2012). Pycnogenol supplementation reduced skin redness from UV rays in a trial of 21 people over 8 weeks. In contrast, almost 20% of the participants on inhalers alone had to increase their dosage. $31.99. Pycnogenol - Herbal Supplements - Healthy Planet Add to Cart. The information in our articles is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. The effect of polyphenolic extract from pine bark, Pycnogenol on the level of glutathione in children suffering from attention deficit hyperactivity disorder (ADHD) [Abstract]. Ginkgo biloba has been widely cultivated across the globe for a variety of uses, most of which are medicinal. Furthermore, when CHS was suppressed by 71% with exogenous treatment with cis-urocanic acid, the putative epidermal mediator of photoimmunosuppression, 0.2% Pycnogenol lotion reduced the immunosuppression to 18%. In contrast, bleeding still occurred in the control group [61]. Can Pycnogenol help? 1) Encourages Healthy Blood Pressure. From diabetes and sexual function to sports performance and beautiful skin, pine bark extract may be worth exploring to provide results youre looking to achieve. Possible side effects . This key chemical, proanthocyanidin, is also found in high concentrations in apples, cranberries, coca, grapes, and red wine. Our team comprises of trained MDs, PhDs, pharmacists, qualified scientists, and certified health and wellness specialists. More research is needed to see how this supplement affects all of these conditions. It has many health benefits, and may help protect against several chronic conditions. Pycnogenol may help with other conditions as well. Depending on the extraction process and the source Pinus species used (P. radiata or P. pinaster), the exact composition will vary. Some research suggests that procyanidins may have antioxidant and anti-inflammatory activity. Another group of men who took just l-arginine didnt improve [66]. The same ingredient can be found in grapeseed oil, the skin of peanuts and witch hazel bark. In a study of 33 people with severe osteoarthritis, pycnogenol (200 mg/day) reduced inflammatory markers after 3 weeks. In 7 volunteers, Pycnogenol (300 mg) for 5 days may reduce the activity of a crucial inflammatory gene (NF-B) [53]. A review was conducted of French maritimepine bark extract, specifically using the nutritional supplement Pycnogenol. In a study of 72 children undergoing cancer chemotherapy, Pycnogenol reduced painful mouth ulcers, both alone and in combination with vitamin E [79]. Potential for allergy when taken orally or used on the skin. In a study of 100 healthy women mostly in their early 40s with mild sexual dysfunction, a combination product with Pycnogenol (Lady Prelox) improved sexual function over 8 weeks [74]. Add to Cart. Systolic blood pressure measures how much blood is pumping from your heart to your arteries. The researchers of the study propose that pycnogenol may reduce pain and cramps during retraining and rehabilitation in people with blood vessel problems [11]. Beta 1-3D Glucan is recognized by cells in the immune system, and can modify your immune system responses. This can cause pain, especially in areas of the body that are used repeatedly, like your hands, fingers, and knees. Pine bark extract may be the perfect treatment since its an antioxidant dynamo. If possible, try to get pine bark extract from a local supplier, such as a health food store. First and foremost, start eating an anti-inflammatory Local Raw Honey (Bee Pollen) Considering how good it tastes, having some raw honey Apple Cider Vinegar (ACV) You can now find high-quality apple cider vinegar in . Extracts can also be made from other pine barks, such as Pinus radiata, Pinus densiflora, Pinus thunbergii, and Pinus massoniana. But, as you know, going for the natural approach can make a huge difference in overall health. Interesting activities, new dishes in restaurants, specialty ingredients, explanations of some netizens questions, etc.Hu Xuan is even helping Fatty s company s tourism manager, managing with Vice President Du Meixin, such as arranging guests reasonably.By the way.Dad, I want to tell you something.I plan to invest in the hotels and entertainment centers in the . Erythritol: Is This Healthy Sweetener the Real Deal? Eye health. Comment * document.getElementById("comment").setAttribute( "id", "a79cdfe7a30d8f84d45d97f833c00b8c" );document.getElementById("a6cbe26769").setAttribute( "id", "comment" ); Save my name, email, and website in this browser for the next time I comment. The following purported benefits of Pycnogenol are only supported by limited, low-quality clinical studies. Pycnogenol (100 mg/day) may reduce hay fever symptoms, according to a clinical trial of 39 people. 5 6 However, evidence is conflictingother studies have shown no effect on the same measures. Pycnogenol, an extract of French maritime pine bark, helps the body fight normal aging by supporting vascular health and healthy circulation. 3. These antioxidants scavenge those damaging free radicals in an effort to eliminate them, ultimately preventing disease. The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. The positive improvements in symptoms were greater among those taking Pycnogenol. The New Pycnogenol Benefits | Dr. Steven Lamm - YouTube During the first month on L-arginine, only five percent of patients experienced normal erection. Eliminate blood clots. We all know the power of antioxidants to improve health and thehigh-antioxidant foodswe should eat regularly. Due to its anti-inflammatory properties, luteolin is being researched as a potential complementary treatment for multiple . Pycnogenol seems well-tolerated for use in adults for up to 6 months. New studies show Pycnogenol can prevent or reverse the oxidative damage that produces blood vessel disease 4, metabolic syndrome 20, diabetes 20,24, and neurodegenerative disorders 23,24. In a double-blind, placebo-controlled, randomized, crossover study, 50 patients with erectile dysfunction (ED) were treated with either L-arginine plus Pycnogenol or placebo for a month. whole-body health. A popular variety is the pinus maritime or the maritime pine that grows exclusively along the coast of southwest France. Moreover, Pycnogenol treatment led to an increase in sperm count and testosterone levels with lowering of blood pressure and cholesterol levels. Pycnogenol Review - Worlds Best Anti-Aging Supplement? Benefits of Pycnogenol - Healthy Directions 5. In one trial of 77 people with type 2 diabetes, pycnogenol (100 mg/day) for 12 weeks lowered both blood sugar levels and HbA1c, a marker of long-term blood glucose levels [31]. The study provided clear evidence that Pycnogenol does, indeed, offer photoprotection however, it came out even better than expected, showing that it may be used to reduce hyperpigmentation of human skin while improving the skin barrier function and extracellular matrix homeostasis. (6). The usual recommended duration of treatment for topical application is 7 days for Pycnogenol cream and 6 weeks for Pycnogenol powder. 10 Ways to Control Blood Sugar without Medication, Pycnogenol (French Maritime Pine Bark Extract): 12 Benefits According to Studies, Reduces leaky blood vessels by making the wall proteins (collagen, elastin) more resistant to damage, Helps maintain high vitamin C and E blood levels for their antioxidant effects, Inhibits platelet aggregation like low-dose aspirin, Reduces hardening in the arteries by increasing nitric oxide production in blood vessels, leading to greater dilatation, Counteracts the damaging effects of ultraviolet radiation, Stimulates the immune system by boosting T and B cell functions, Protects brain cells from toxic chemicals. According to research, Pycnogenol may have a multitude of health benefits, which are likely due to this extracts antioxidant and anti-inflammatory properties. Researchers suggest that Pycnogenol may reduce cough, night-awakenings, improve airway flow, and the need for additional asthma medication [16]. A 2004 animal study also found that applying a gel containing pine bark extract sped up the wound-healing process. A small 2012 study on postmenopausal women found that pine bark extract improved hydration and elasticity of skin. Consequently, blood pressure is lowered. Thirty patients were treated with 150 mg of Pycnogenol a day and the other 10 patients with placebo for a period of two months. (2017). Chronic Obstructive Pulmonary Disease (COPD) is a chronic lung disease caused primarily by tobacco use. 2005 - 2023 WebMD LLC. A high number signals high blood pressure. Reduces Pain. DOI: Marini A, et al. Information is shared for educational purposes only. Moreover, Pycnogenol treatment reduced the use of painkillers. In a clinical trial of 116 women, Pycnogenol (60 mg/day) reduced menstrual pain and the need for additional painkillers, taken over 2 cycles. The women taking Pycnogenol also experienced improvement in fatigue, sleep, concentration, memory, dizziness, and mood, including less irritability. In a clinical trial of 92 people with tinnitus, or ringing in the ears, Pycnogenol (100-150 mg/day) helped reduce symptoms and improve blood flow in the ears after 4 weeks [80]. According to some researchers, Pycnogenol may lower blood pressure by relaxing blood vessels, reducing free radicals, and lowering inflammation. Masquelier was easily able to create a pine bark extract from materials that were otherwise known as waste. 7. Tongkat ali is an herbal remedy suggested to treat various ailments, including low testosterone and male infertility. Pain score in the Pycnogenol-treated group was reduced by 56%, as compared to 9.6% reduction in the placebo group. Blood clots form as a result of platelet aggregation, which is the platelets in the blood clumping together. Pycnogenol (125 mg/day) had the same effects in another study of 48 people with diabetes and high blood pressure. In the study, many of the participants on Pycnogenol reduced their dosage of high-blood-pressure medication (nifedipine) [37]. In one clinical trial of 156 osteoarthritis patients, pycnogenol reduced pain, stiffness, swelling, and improved joint function after 3 months. Symptoms of menopausal syndrome, also known as climacteric syndrome, include: hot flashes; chills; headache; and depression. Vinpocetine is used to increase brain circulation, alertness, cognitive function, concentration, and memory, as well as to lower inflammation and oxidative stress.This article will explore vinpocetine's history, how it works, its potential benefits, and any possible safety issues . Staves Off Infections. Top 10 Health Benefits of Nattokinase - Earth Clinic $109.99. Pycnogenol is thought to be an antioxidant that helps protect cells from damage. A randomized, double-blind, placebo-controlled study of 60 patients aged six to 18 years old, was conducted over three months during which patients were randomly assigned to receive either Pycnogenol or placebo. Ask your doctor for advice. A 10 week clinical trial with 30 children shows that Pycnogenol may improve symptoms of Crohns disease. Set Ascending Direction. Pycnogenol: Health Benefits, Uses, Doses, Safety Information - WebMD Disease of the retina in the eye. It also may help those on blood pressure medications to reduce their dose [32]. Pycnogenol (100 mg/day) may reduce leg swelling, spider veins, and cramps according to a study of 133 women with varicose veins who recently gave birth. Proper nutrition is essential for ADHD treatment. Neuroprotective effect of Pycnogenol® following traumatic brain injury. Some studies have suggested it may modestly improve blood pressure, cholesterol, and C-reactive protein. The 2012 study on the anti-aging benefits of Pycnogenol is commonly-cited by anti-aging supplement manufacturers. In 19 smokers, increased platelet aggregation was more significantly reduced by 200 mg than either 10 mg or 100 mg of Pycnogenol. Last medically reviewed on January 24, 2018. Your email address will not be published. A deficiency can cause issues like anemia, stunted growth, heart problems and neural tube defects. Pycnogenol is not approved by the FDA for medical use. It also provides powerful antioxidant protection and helps inhibit inflammatory factors to support. A 2015 review indicates that pine bark extract can be used to treat metabolic syndrome and related disorders such as obesity, diabetes, and high blood pressure. However, in all the above studies insulin levels did not change. Pine bark extract offers some amazing benefits since its so high in powerful antioxidants. WebMD does not provide medical advice, diagnosis or treatment. Pycnogenol accelerates wound healing and reduces scar formation [Abstract]. Pycnogenol was featured on The Dr. Oz Show in January 2013, . Studies have also safely used Pycnogenol in children and during pregnancy. Enzogenol also may reduce mental fatigue and sleep problems [82]. In this study, 155 peri-menopausal women were enrolled in a double-blind, placebo-controlled study. (3), Ototoxicity is ear poisoning and can occur when exposed to certain drugs or chemicals, such as cisplatin, that damage the inner ear or the vestibulocochlear nerve. Prenatal nutrition can be confusing. Protection from inflammation, immunosuppression and carcinogenesis Circulation and Jet Lag on Long Flights. According to a large analysis, Pycnogenol may reduce osteoarthritis symptoms and pain short-term [45, 46]. Dizziness. A trial of 84 people found that both Pycnogenol oral supplements and creams (0.5%) may prevent hemorrhoids from bleeding during acute attacks after 7 days. Not bad. Amazon.com: Healthy Origins Pycnogenol 100 mg (Nature's Super Plus, it reduced total and LDL (bad) cholesterol. Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. Pycnogenol has given indications that it might be able to benefit heart and artery health, to include reducing high blood pressure. Pine bark extract contains active ingredients that can also be found in peanut skin, grape seed, and witch hazel bark. Pycnogenol (100 mg/day) supplementation may decrease symptoms of the common cold and speed up recovery, according to a clinical trial of 146 people. In those treated with Pycnogenol, the edema score was increased by 17.9% versus an increase of 58.3% in the control group. Pycnogenol-treated patients reported significant improvement with knee pain, as compared to the placebo group. Known for its antioxidant properties, Pycnogenol offers a wide range of potential health benefits. ", Mayo Clinic: High blood pressure (hypertension)., Panminerva Medica: "Pycnogenol improvements in asthma management. However, it can also be used topically. Unlike drug manufacturers, the makers of supplements dont have to show their products are safe or effective before selling them on the market. A 2017 review reported on the many benefits of using pine bark extract to reduce the effects of aging on skin. According to researchers, it may help prevent the rise in free radicals typically seen after exercise, which could cause muscle fatigue and damage [9]. It can also be found as creams, lotions or ointments, typically containing 0.5 percent to 2 percent pine bark extract. According to the National Institutes of Health, its safe for adults to take 50 to 450 milligrams of pine bark extract daily for up to one year. Purity and potency of Pycnogenolare continuously monitored . Memorial Sloan-Kettering Cancer Center web site: "About Herbs: Pine Bark Extract. In a study of 20 postmenopausal women, 12 weeks of pycnogenol supplementation improved hydration and elasticity of the skin. In one human study, some of the reported side effects of chanca piedra supplementation included: abdominal pain. In one study, people with high blood pressure were examined to see how the supplement impacted their blood pressure. 1 Anti-Aging Beverage, An surprisingstudy found that pine bark extract was far better than aspirin at inhibiting smoking-induced clotting, using lower amounts without the bleeding often found when using aspirin. Results failed to show any efficacy of Pycnogenol or methylphenidate when compared to placebo. Patients were given 100 milligrams of Pycnogenol, a branded version of pine bark extract, for 12 weeks, with continued anti-diabetic treatment. The results of a 2013 animal study suggest that pine bark extract may help to reduce damage to nerve cells following a traumatic brain injury. Pycnogenol may reduce glucose levels, but it doesnt appear to increase insulin production or insulin sensitivity. Debra Rose Wilson, PhD, MSN, RN, IBCLC, AHN-BC, CHT. In another study, 61 children with ADHD were given one mg per kg/day of Pycnogenol or placebo over four weeks. Pycnogenol may stimulate the immune system. Four hundred years later, a French researcher named Jacques Masquelier did some studies to understand why this natural remedy was so effective. In a smaller study of 58 people, pycnogenol reduced the inflammatory marker CRP [49, 50]. Research suggests that taking pycnogenol improves mental function and memory in both young adults and the elderly. The active ingredients in pycnogenol can also be extracted from other sources, including peanut skin, grape seed, and witch hazel bark. The Many Benefits of Grape Seed Extract - Mercola.com Another study found this supplement can even halt progression of vision . Enzogenol, a slightly different pine bark extract, improved cognitive function in a clinical trial of 42 older men after 5 weeks of supplementation [23]. You can refer to the National Institutes of Healths dosage guidelines for specific conditions. A 2011 study by Dr. G. Belcaro concluded, " Pycnogenol administration was effective for better control of signs and symptoms of allergic asthma and reduced the need for medication". In another study, 45 men with ED were given 1.7 grams of L-arginine a day during the first month, 40 mg Pycnogenol twice daily during the second month, and the dose increased to three 40-mg Pycnogenol doses daily during the third month. Pine bark extract can help reduce muscle soreness and may help improve conditions relating to poor circulation, high blood pressure, osteoarthritis, diabetes, ADHD, female reproductive issues, skin, erectile dysfunction, eye disease and sports stamina. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition. In a good-quality study, 100 patients with osteoarthritis of the knee were treated for three months either with 150 mg of Pycnogenol a day or placebo. Pycnogenol (150 mg/day) reduced pain in a study of 100 people with osteoarthritis after 3 months. Results showed that one month of Pycnogenol led to a significant reduction of hyperactivity with improvement in attention and visual-motor coordination and concentration, as compared to no positive effects in the placebo group. Regardless of what youre using it for, its best to start with the lowest possible dose. (10), A 15-year Dutch study was published stating that 27,939 healthy female health professionals were given aspirin or a placebo for a period of time. 7. The specific tree from which the bark is extracted is called a maritime pine. Pycnogenol has four main components that contribute to its benefits for men's health. Its true. However, these studies appear to be methodologically sound and reliable, with no blatant errors in the study design and data collection. A trial of 39 people with hay fever found that Pycnogenol may reduce nose and eye symptoms. Eighty-six patients were treated either with Pycnogenol at 150 mg or 300 mg daily or the drugs diosmin and hesperidin (Daflon)at 1,000 mg daily for two months. Importantly, all studies found that Pycnogenol has to be taken at least 5 weeks before the allergy season in order to see potential benefits, with the best results in those who take it 7-8 weeks ahead. All of our content is written by scientists and people with a strong science background. A clinically studied blend of Pycnogenol and a special bilberry extract (called Mirtogenol ) has been shown to provide benefits for vision and eye health. A small 2017 study examined the effects of pine bark extract in treating cardiovascular risk factors associated with menopause. 1. Pycnogenol: Skin, ADHD, Other Uses, Side Effects - Healthline Pycnogenol treatment led to significantly better improvement in the lung function and asthma symptoms. Mental function. Potential benefits of folic acid include a reduced risk of cancer, improved cognitive function, stronger bones, enhanced heart health, better pregnancy outcomes and reduced symptoms of restless legs syndrome. Diarrhea. In addition to OPC, grape seed extract contains linoleic acid, flavonoids and phenolic procyanidins that help protect and strengthen capillaries, blood vessels, veins and arteries, which can then improve blood circulation. DIM and other plant indoles are found in . Note that the numbers in parentheses (1, 2, etc.) They are continually monitored by our internal peer-review process and if we see anyone making material science errors, we don't let them write for us again. According to some researchers, when you take Pycnogenol [8]: Research suggests that Pycnogenol may protect cells in the body against oxidative stress. A study with four groups of 30 patients each were studied: (1) systemic Pycnogenol and local application; (2) local Pycnogenol only; (3) oral Pycnogenol and (4) medications only (control).
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